Rapid Fire Australian Epidemiology Association ASM 2018

Using Growth-Mixture Modeling to reveal hidden decay-of-impact trajectories after health education (#159)

MJ Park 1 , Joseph Green 2 , Yoon Soo Park 3
  1. College of Nursing, Konyang University, Daejeon, South Korea
  2. Graduate School of Medicine, University of Tokyo, Tokyo, Japan
  3. Department of Medical Education, University of Illinois at Chicago, Chicago, IL, USA

Background

Programs for teaching self-management skills to people with chronic diseases can reduce anxiety and depression, but those benefits appear to be small.

 

Aim

We tested the hypothesis that important differences among the program’s participants are “averaged out” in summary statistics – that the benefits are actually large for some participants and small for others.

 

Methods

Adults with various chronic diseases (n=456) participated in the Chronic Disease Self-Management Program. We focused on two of the many outcome indicators: anxiety and depression. Both were measured four times over one year. To reveal latent trajectories – distinct patterns of change over time – we used Growth-Mixture Modeling (GMM) and the Bayesian information criterion.

 

Results

GMM identified two trajectories. One trajectory began from a low-anxiety baseline, and it showed almost no change. The other trajectory began from a clinically important high-anxiety baseline, and it showed marked improvement, but that improvement was followed by deterioration back to the baseline level, i.e. decay of impact. Almost half of the participants (46%) had the decay-of-impact trajectory. The results for depression were similar (51%).

 

Conclusion

First, GMM identified two distinct trajectories of change in anxiety and depression after a health-education intervention. Second, about half of the participants had a large decay of impact. If those people can be identified early, then “booster-session” reinforcements can be offered to them specifically, to help them maintain their new self-management skills. GMM can change the way these programs are evaluated, directing attention away from overall averages and toward pattern-defined groups.

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  1. Muthén, B. (2004) Latent variable analysis: Growth mixture modeling and related techniques for longitudinal data. In D. Kaplan (ed.), Handbook of quantitative methodology for the social sciences (pp. 345-368). Newbury Park, CA: Sage Publications.
  2. Green LW. (1977) Evaluation and measurement: some dilemmas for health education. Am J Public Health. 67(2): 155–161.
  3. Park MJ, Green J, Ishikawa H, and Kiuchi T. (2013) Hidden decay of impact after education for self-management of chronic illnesses: hypotheses. Chronic Illness. 9(1): 73–80. doi: 10.1177/1742395312453351
  4. Park MJ, Green J, Ishikawa H, Yamazaki Y, Kitagawa A, Ono M, et al. (2013) Decay of Impact after Self-Management Education for People with Chronic Illnesses: Changes in Anxiety and Depression over One Year. PLOS ONE 8(6): e65316. https://doi.org/10.1371/journal.pone.0065316